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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
12.5 DPC

17 matching records from 17 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Hoxa11  homeobox A11   (Synonyms: Hox-1.9, Hoxa-11)
Results  Reference
1J:62547 Barna M, Hawe N, Niswander L, Pandolfi PP, Plzf regulates limb and axial skeletal patterning. Nat Genet. 2000 Jun;25(2):166-72
1J:283343 Bastida MF, Perez-Gomez R, Trofka A, Zhu J, Rada-Iglesias A, Sheth R, Stadler HS, Mackem S, Ros MA, The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1090-1096
1J:231885 Beccari L, Yakushiji-Kaminatsui N, Woltering JM, Necsulea A, Lonfat N, Rodriguez-Carballo E, Mascrez B, Yamamoto S, Kuroiwa A, Duboule D, A role for HOX13 proteins in the regulatory switch between TADs at the HoxD locus. Genes Dev. 2016 May 15;30(10):1172-86
1J:308920 Bolt CC, Lopez-Delisle L, Mascrez B, Duboule D, Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations. Nat Commun. 2021 Aug 18;12(1):5013
1*J:103688 Challen G, Gardiner B, Caruana G, Kostoulias X, Martinez G, Crowe M, Taylor DF, Bertram J, Little M, Grimmond SM, Temporal and spatial transcriptional programs in murine kidney development. Physiol Genomics. 2005 Oct 17;23(2):159-71
1*J:98919 Cobb J, Duboule D, Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia. Development. 2005 Jul;132(13):3055-67
1*J:46141 Hostikka SL, Capecchi MR, The mouse Hoxc11 gene: genomic structure and expression pattern. Mech Dev. 1998 Jan;70(1-2):133-45
1J:239414 Kherdjemil Y, Lalonde RL, Sheth R, Dumouchel A, de Martino G, Pineault KM, Wellik DM, Stadler HS, Akimenko MA, Kmita M, Evolution of Hoxa11 regulation in vertebrates is linked to the pentadactyl state. Nature. 2016 Nov 03;539(7627):89-92
1*J:161758 Kiefer SM, Robbins L, Barina A, Zhang Z, Rauchman M, SALL1 truncated protein expression in Townes-Brocks syndrome leads to ectopic expression of downstream genes. Hum Mutat. 2008 Sep;29(9):1133-40
1*J:287563 Mercader N, Selleri L, Criado LM, Pallares P, Parras C, Cleary ML, Torres M, Ectopic Meis1 expression in the mouse limb bud alters P-D patterning in a Pbx1-independent manner. Int J Dev Biol. 2009;53(8-10):1483-94
1J:137524 Mugford JW, Sipila P, Kobayashi A, Behringer RR, McMahon AP, Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo. Dev Biol. 2008 Jul 15;319(2):396-405
1J:217206 Neufeld SJ, Wang F, Cobb J, Genetic interactions between Shox2 and Hox genes during the regional growth and development of the mouse limb. Genetics. 2014 Nov;198(3):1117-26
1J:181230 Scotti M, Kmita M, Recruitment of 5' Hoxa genes in the allantois is essential for proper extra-embryonic function in placental mammals. Development. 2012 Feb;139(4):731-9
1*J:204375 Sheth R, Bastida MF, Kmita M, Ros M, "Self-regulation," a new facet of Hox genes' function. Dev Dyn. 2014 Jan;243(1):182-91
1J:197026 Sheth R, Gregoire D, Dumouchel A, Scotti M, Pham JM, Nemec S, Bastida MF, Ros MA, Kmita M, Decoupling the function of Hox and Shh in developing limb reveals multiple inputs of Hox genes on limb growth. Development. 2013 May;140(10):2130-8
1*J:241982 Woltering JM, Noordermeer D, Leleu M, Duboule D, Conservation and divergence of regulatory strategies at Hox Loci and the origin of tetrapod digits. PLoS Biol. 2014 Jan;12(1):e1001773
1J:175770 Wyngaarden LA, Delgado-Olguin P, Su IH, Bruneau BG, Hopyan S, Ezh2 regulates anteroposterior axis specification and proximodistal axis elongation in the developing limb. Development. 2011 Sep;138(17):3759-67

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory